3B Medical Luna II CPAP / Auto CPAP

How to set up the 3B Medical Luna II CPAP / Auto CPAP

From the box to your first night. Keep the user guide that came with your machine nearby: if anything here differs from it, follow the guide.

Check the box
Look for the device, two air filters, power adapter, power cord, tube, carrying case and documents, plus the SD card if included. Call your supplier if something is missing.
Place it below head height
Use a firm, flat surface lower than your head, clear of curtains, heaters and bedding.
Install the filter
With the machine unplugged, put the air filter in the filter cap and fit the cap to the back of the device. Never run it without a filter.
Connect power
Plug the adapter into the DC inlet on the back, connect the power cord and plug into the wall.
Fill the humidifier (if you have one)
Fill the water chamber with distilled water no higher than the max line, about 360 mL, and seat it. Do not tilt the machine with water in it.
Connect tubing and mask
Push the tube onto the air outlet and connect your mask to the other end. If you have a ComfortLine heated tube, set it up with its own power supply as its instructions describe.
Insert the SD card
If you have one, slide it in until the correct-insertion symbol shows. Remove it only when airflow is off.
Set comfort options
Hold the Ramp button for three seconds to open the patient menu and set humidity, ramp time, mask type and the clock.
Start therapy
Put on your mask, lie down and press the knob to start airflow. Adjust the headgear for a seal without overtightening. To stop, take the mask off and hold the knob for two seconds.

After setup: settings worth knowing

Humidifier: Sets the heated humidifier from Off to 1 to 5; the number of lit blue lights on the front matches the level.
Ramp: Drops pressure and climbs back to your prescription over the ramp time; adjustable in 5 minute steps. Press the Ramp button any time during the night to restart it. Ramp is not prescribed for everyone.
RESlex: Exhalation relief, Off or 1 to 3. The manual says it is enabled by your home care provider, so if you cannot change it, ask them.
Delay (dry-out): With the humidifier on, keeps air flowing at about 2 cm H2O for about 15 minutes after you stop, to dry the chamber.
Mask Type: Selects Full Face, Nasal, Pillow or Other so the machine knows your mask.
Brightness and time: Screen brightness High or Low, and the clock.

Distilled water is what most CPAP humidifier chambers are meant to be filled with, because it leaves little or no mineral scale behind.

The air inlet filter keeps dust and lint out of the machine and your airway; it is a cheap part that needs regular replacement.

Heated CPAP tubing

Tubing with a built-in heating wire that keeps humidified air warm all the way to the mask, which is the main fix for rainout (water droplets …

The removable water tank of a CPAP humidifier; it wears and needs replacing, especially if it cracks, clouds or leaks.

The plain hose between the machine and the mask; it wears out and should be replaced on a regular schedule.

CPAP tubing cover

A fabric sleeve that slips over CPAP tubing to insulate it, reduce condensation and make the hose feel softer against your skin.

CPAP chinstrap

A soft strap that supports the jaw to help keep the mouth closed, used mainly with nasal and nasal pillow masks to reduce mouth leaks.

Plain, mild dish soap is the cleaning agent most CPAP makers and the FDA point to for masks, tubing and humidifier chambers.

Last reviewed October 11, 2026. How we research · Report an error