React Health Luna G3 BPAP 25A

How to set up the React Health Luna G3 BPAP 25A

From the box to your first night. Keep the user guide that came with your machine nearby: if anything here differs from it, follow the guide.

  1. Unpack and check the box

    Look for the main device, power adapter, power cord, power cord locker, reusable air filter, carrying case and documents, plus tubing or heated tubing, SD card and cellular module if your supplier included them. If something is missing, call your supplier before the first night.

  2. Place it lower than your head

    Set it on a firm, flat nightstand below head height, away from heaters, vents and curtains, with the air inlet clear of bedding.

  3. Fit the filter

    With the machine unplugged, attach the reusable filter to the filter cap (with the optional white ultra-fine filter on the machine side if you use one) and snap the cap on.

  4. Connect power and the cord locker

    Plug the adapter into the DC inlet, connect the power cord, and plug into the wall. Clip the narrow end of the power cord locker onto the adapter cable, fit it into the buckle at the DC inlet and press it down so the plug cannot work loose.

  5. Fill the water chamber

    Fill with distilled water to no higher than the max line, about 360 mL, close the cap and seat the chamber. Do not tilt the machine once it has water in it.

  6. Attach tubing and mask

    Connect tubing or heated tubing to the air outlet; for heated tubing, also push its plug into the heated tubing port. Connect the mask to the other end.

  7. Check your settings screen

    Your provider will have set the mode (for example AutoS) and pressures. Confirm the main screen looks the way your supplier showed you; if the mode or pressures look wrong, call them before you start.

  8. Set comfort options

    Use the knob to open Initial Setup and set Humidifier, Heated Tubing, Ramp, Mask Type and the clock.

  9. Start therapy

    Put on the mask, lie down and press Start/Stop or breathe into the mask. You should feel the pressure rise as you breathe in and drop as you breathe out. If breathing feels out of sync, you feel short of breath, or you get chest pain or severe headache, stop and contact your clinician.

After setup: settings worth knowing

  • Humidifier: Moisture level: Off, Auto or 1 to 5.
  • Preheat: Warms the water before bed; turns itself off after 30 minutes.
  • Heated Tubing: Warms the hose to cut rainout, Off or 1 to 5. Only shows when a heated tube is connected.
  • Ramp: Starts at lower pressure and climbs to your prescribed pressures over the set time, in 5 minute steps or Auto.
  • RESlex: Lowers pressure as you exhale, Off or 1 to 3. The manual describes it as a feature your physician enables; if you cannot change it, ask your clinician.
  • Delay (dry-out): Keeps air flowing at about 2 cm H2O for around 15 minutes after you stop, to dry the humidifier.
  • Mask Type and Mask Fitting Test: Selects Full Face, Nasal, Pillow or Other and checks your seal with a "great" or "need to adjust" result.
  • Accessories reminder: Sets filter, tubing and mask reminders (30 days, 60 days, 180 days, 1 year or Off) and resets the timers.

How to change each one →

Supplies that can help

Distilled water for CPAP humidifiers

Distilled water is what most CPAP humidifier chambers are meant to be filled with, because it leaves little or no mineral scale behind.

Replacement CPAP air filters

The air inlet filter keeps dust and lint out of the machine and your airway; it is a cheap part that needs regular replacement.

Heated CPAP tubing

Tubing with a built-in heating wire that keeps humidified air warm all the way to the mask, which is the main fix for rainout (water droplets …

Humidifier water chamber (tub)

The removable water tank of a CPAP humidifier; it wears and needs replacing, especially if it cracks, clouds or leaks.

CPAP tubing cover

A fabric sleeve that slips over CPAP tubing to insulate it, reduce condensation and make the hose feel softer against your skin.

CPAP chinstrap

A soft strap that supports the jaw to help keep the mouth closed, used mainly with nasal and nasal pillow masks to reduce mouth leaks.

CPAP hose cleaning brush

A long, flexible brush sized to reach the full length of CPAP tubing so you can scrub the inside, not just soak it.

Mild unscented soap for CPAP cleaning

Plain, mild dish soap is the cleaning agent most CPAP makers and the FDA point to for masks, tubing and humidifier chambers.

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Sources

Last reviewed October 11, 2026. How we research · Report an error